Once you’re in menopause, your hormones shift and estrogen ranges drop, which results in sizzling flashes, temper swings and weight acquire. The additional kilos might be troublesome to lose and the very last thing you need is one thing to disrupt your hormones much more. To assist do away with the cussed extra weight, many ladies flip to intermittent fasting, which aids in weight administration targets.
For years, 16/8 has been the favored strategy–you quick for 16 hours and eat solely throughout an eight-hour window, however there’s one other fasting technique specialists desire. It’s known as modified fasting or the 14/10 technique, the place you quick for 14 hours and eat throughout a 10-hour interval, and it’s simpler in your physique whereas producing outcomes.
“For ladies over 45, the 14/10 fasting technique provides a delicate, sustainable strategy to reap the metabolic and cognitive advantages of intermittent fasting with out triggering hormonal disruption,” says Jason Itri, MD, PhD, Founder at Longevity Well being Clinic.
He explains, “It aligns nicely with circadian biology, helps insulin regulation, and helps protect sleep, temper, and vitality, all essential throughout midlife transitions.” He provides, “It is probably not as hardcore as 16/8, however usually works higher in follow for real-world outcomes.
Right here’s every part to learn about modified fasting and why it really works after 40 with out impacting your hormones.
What Ought to Ladies Know About Intermittent Fasting


Intermittent fasting works, however there are issues to bear in mind.
“Intermittent fasting shouldn’t be a one-size-fits-all strategy, particularly for girls over 45,” says Dr. Itri. “Throughout this life stage, hormonal shifts related to perimenopause and menopause (declines in estrogen, progesterone, testosterone, and typically thyroid hormones) can influence how the physique responds to fasting.”
Dr. Itri notes that ladies are delicate to fasting and pointed to a 2021 assessment in Vitamin Opinions that highlights {that a} “girls’s hormonal methods, together with the hypothalamic-pituitary-adrenal (HPA) axis, are extra delicate to caloric restriction, which can have an effect on cortisol and insulin regulation in another way than in males.”
One other factor to contemplate is timing and stress. In response to Dr. Itri, intermittent fasting “might have an effect on cortisol ranges, and for girls susceptible to stress or adrenal dysregulation, aggressive fasting can backfire (e.g., fatigue, sleep points, hormone imbalances).”
The part of menopause additionally issues with intermittent fasting.
“For premenopausal girls, fasting tolerance might differ relying on cycle part, typically higher tolerated within the follicular part than luteal,” says Dr. Itri.
Distinguishing Options of Modified Fasting


The 14/10 fasting mannequin is really helpful by medical doctors for a number of causes, per Dr. Itri.
Much less aggressive than 16/8: It supplies the metabolic advantages of fasting whereas minimizing hormonal stress.
Extra sustainable: Simpler adherence resulting from diminished starvation and fewer way of life disruptions.
Circadian-aligned: Usually higher synchronized with pure daylight rhythms, supporting glucose management and metabolism.
How Efficient Modified Fasting Is It In comparison with 16/8


There was extra analysis finished on 16/8 fasting; nevertheless, there’s rising assist for girls making an attempt the modified fasting technique as a result of proof that exhibits it’s efficient, per Dr. Itri.
- A 2020 Cell Metabolism research (Wilkinson et al.) in metabolic syndrome sufferers confirmed that even 10-hour time-restricted consuming improved weight, blood stress, and ldl cholesterol inside 12 weeks.
- A 2022 assessment in Weight problems Opinions emphasised that reasonable TRF (time-restricted feeding) like 14/10 can obtain comparable metabolic advantages to 16-8 when sustained over time, particularly if meals high quality is excessive.
- A pilot research in girls (Jamshed et al., 2019) indicated {that a} much less restrictive window preserved sleep high quality and diminished cortisol elevation, key issues for midlife girls.
Backside line: For ladies over 45, 14/10 could also be almost as efficient for metabolic well being as 16-8, however with decrease hormonal disruption and higher adherence.
Advantages of Modified Fasting for Ladies 45+


Ladies of their 40s and 50s face an elevated danger of insulin resistance, weight acquire, cognitive decline, and irritation. 14-10 fasting can tackle these with out overburdening the physique, based on Dr. Itri.
Improved insulin sensitivity: TRF reduces glucose variability and fasting insulin, key for stopping metabolic syndrome.
Decreased irritation: Time-restricted consuming has been proven to decrease CRP and pro-inflammatory cytokines (e.g., TNF-α, IL-6).
Assist for circadian rhythms: Consuming in sync with pure gentle cycles improves melatonin manufacturing and sleep high quality—usually disrupted in midlife girls.
Hormonal steadiness: Not like extended fasts, the 14-10 strategy avoids extreme stress hormone spikes whereas encouraging mitochondrial autophagy.
Weight regulation with out calorie counting: Research (e.g., Gabel et al., 2018) present that TRF promotes spontaneous caloric discount and fats loss, even with out weight-reduction plan monitoring.
Errors to Keep away from When Fasting


There are quite a lot of causes to attempt fasting, however to get the complete advantages, Dr. Itri says girls over 45 ought to keep away from these errors.
- Overfasting or fasting too often
- Pushing to 18+ hour fasts day by day can increase cortisol and negatively influence thyroid and intercourse hormones.
- Skipping breakfast and consuming late
- Early consuming home windows (e.g., 8 AM–6 PM) are extra favorable for metabolic outcomes than late-night consuming, which might disrupt sleep high quality.
- Poor nutrient density
- It isn’t a license to eat something. Entire meals, protein, fiber, and wholesome fat are important for satiety and hormone well being.
- Not adjusting for exercise or stress
- Ladies with excessive bodily or emotional stress may have extra gasoline, particularly round exercises.
- Neglecting electrolytes and hydration
- Even throughout shorter fasts, guarantee sodium, potassium, and magnesium wants are met to keep away from fatigue and complications.